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#1
09-29-2009, 10:39 PM
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Satellite Cell activation may not be necessary for muscle hypertrophy
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TEAM NORTON The"Outwork" mindset changed my entire life, perhaps it can help you as well Muscle Hypertrophy occurs independent of exercise intensity 
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#2
09-29-2009, 10:43 PM
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any thoughts Gabe/Jacob or anybody else? i for one found it very interesting.
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TEAM NORTON The"Outwork" mindset changed my entire life, perhaps it can help you as well Muscle Hypertrophy occurs independent of exercise intensity
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#3
09-30-2009, 12:25 PM
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forgive me if I mess this up...
satellite cell activation, that is basically induced from high mechanical stress right? Like emphasis on eccentrics, stretch position exercises, etc? I really tried to look up AKT, but I couldn't find much that I could understand without spending too much time at work...  Is the study saying that maybe hypertrophy can be induced without as much stress/damage as previously thought through the satellite cell pathway?
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 James 1:16-17 ESV Do not be deceived, my beloved brothers. Every good gift and every perfect gift is from above, coming down from the Father of lights With God's help...Mens sana in corpore sano
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#4
09-30-2009, 10:52 PM
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This is jakes field of expertise, so I just refer to him for questions like these. I told him about it so hopefully he can respond.
He told me you don't have to have satelite cell activation for newbies; but for monsters like you guys, it is likely required. AKT I am familiar with and research in my lab. It is an upstream target of the mTOR pathway, which can increase muscle protein synthesis. Appears to be stimulated by insulin and exercise/growth factors. My research so far has not shown much evidence for leu working through this pathway to stimulate mTOR. But I digress...
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Gabriel "Venom" Wilson, Ph.D. Nutritional Sciences B.S. (Hons) & M.S. in Kinesiology, CSCS Vice President, ABCbodybuilding Co-Editor. of JHR Venom@abcbodybuilding.com Bible Studies Click Here to Support the Future of Bodybuilding! Matthew 7:20 And Jesus said unto them, Because of your unbelief: for verily I say unto you, If ye have faith as a grain of mustard seed, ye shall say unto this mountain, Remove hence to yonder place; and it shall remove; and nothing shall be impossible unto you.
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#5
10-02-2009, 09:08 PM
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Quote:
__________________
TEAM NORTON The"Outwork" mindset changed my entire life, perhaps it can help you as well Muscle Hypertrophy occurs independent of exercise intensity
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#6
10-02-2009, 09:15 PM
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Again, elderly is jakes area of expertise. I'll see if I can get him...
__________________
Gabriel "Venom" Wilson, Ph.D. Nutritional Sciences B.S. (Hons) & M.S. in Kinesiology, CSCS Vice President, ABCbodybuilding Co-Editor. of JHR Venom@abcbodybuilding.com Bible Studies Click Here to Support the Future of Bodybuilding! Matthew 7:20 And Jesus said unto them, Because of your unbelief: for verily I say unto you, If ye have faith as a grain of mustard seed, ye shall say unto this mountain, Remove hence to yonder place; and it shall remove; and nothing shall be impossible unto you.
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#7
11-21-2012, 12:55 PM
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myostatin and serum response factor
Thought I would contribute a couple of references I thought relevant to the discussion. First, myostatin deficient mice had hypertrophy prior to satellite cells recruitment.
http://www.ncbi.nlm.nih.gov/pubmed/22393251 It seems to add credence to the the theory of satellite cells being required to keep the DNA/protein ratio within certain limits. Also, it seems that SRF or serum response factor is involved in this. http://www.plosone.org/article/info%...l.pone.0003910 Hope this helps! 
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