ABCbodybuilding - View Single Post - Satellite Cell activation may not be necessary for muscle hypertrophy
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Old 11-21-2012, 01:55 PM
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Join Date: Nov 2012
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Default myostatin and serum response factor

Thought I would contribute a couple of references I thought relevant to the discussion. First, myostatin deficient mice had hypertrophy prior to satellite cells recruitment.
http://www.ncbi.nlm.nih.gov/pubmed/22393251
It seems to add credence to the the theory of satellite cells being required to keep the DNA/protein ratio within certain limits.

Also, it seems that SRF or serum response factor is involved in this.

http://www.plosone.org/article/info%...l.pone.0003910

Hope this helps!
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