ABCbodybuilding - View Single Post - Diet for obese vs. lean individuals - insulin sensitivity
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Old 06-03-2009, 12:36 AM
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Absolutely, being in a caloric surplus is important for getting huge. This post was centered on people cutting, though.

About insulin sensitivity, more insulin does not = more effective response from insulin. Obese get constant supplies of insulin in the blood. But studies show they are actually less anabolic, and don't stimulate muscle protein synthesis as potently in response to a meal as lean people. Why? One reason is because they are insensitive to anabolic factors like insulin.

The point of insulin sensitivity, is that you require less insulin to get a maximal response - so with half the amount of insulin, a lean person can dispose of the same amount of glucose as an overweight person (just threw out a general number there). Same thing applies for anabolic factors like IGF.

So insulin sensitivity is a good thing...
Gabriel "Venom" Wilson, Ph.D. Nutritional Sciences
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