Re: Growth hormone and muscle function responses to skeletal muscle ischemia.
I think the mechanism has something to do with lactic acid and GH. I believe the GH response to resistance exercise is proportional to the lactic acid accumulation (but don't quote me on this).
I would probably wait to try this until it is time to deload for a week or two. I've talked to Layne (he sent me these articles originally) and he said he has tried it. He tied a belt around his legs when he was doing leg extensions (I think maybe hack squats too) and he had to lighten the weight quite a bit.