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Old 09-19-2006, 12:02 AM
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Default Glycogenolysis in non active muscle during exercise? What could be the reason???

Fellow colleagues,

The question is in regards to glycogenolysis, or the breakdown of glycogen to form either pyruvate or lactic acid. We of course discuss this in the following article

http://www.abcbodybuilding.com/energetic2.pdf

Glycogenolysis is critical to exercise performance, and as exercise intensity increases we become more and more reliant on this energy pathway. Further, depletion of glycogen levels leads to fatigue, and decreased performance. In fact, in individuals with Mccardles disease, who cannot break down glycogen, they only attain 50 % of the maximal values during exercise as compared to normal individuals. But this is because glycogen powers contraction in 'active muscle tissue'


Question
here is an interesting finding. While this does not occur all the time, during some prolonged exercise, such as one leg cycling, there has been doccumented as much as a 20 % decrease in muscle glycogen in the non active leg. But why is this the case?

Thats what I would like to hear your insights on!
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