Losing weight
 

Where is the first part of the body that you notice weight loss first?

From experience, you first lose it from where you have the most.
After that, it's hard to say, for me, once I've lost a decent amount of weight, then I start to lose it in my face.

Ironically, the first place to lose it from (where you have the most) is also usually the last place as well. Meaning, that although you will get leaner there, there also tends to be some stubborn fat there as well.