Just Say No To Soy!
 

So Layne emailed me this article the other day

http://diabetes.diabetesjournals.org...full/57/5/1176

Basically it demonstrates that Soy increases AMPK activity, which is a negative regulator of mTOR, which itself is the main stimulator of skeletal muscle protein synthesis :eek:

So not only is Soy low in leucine content, but it actually inhibits protein synthesis!

eew! DEATH TO SOY!

is this the processed soy protein powder? or the soy bean? Because i know the fda requires manufactures to supplement the powder with aminos...

this also goes along what we are told by docs over here in the uk, soy protien decreases mens test aswell as fertility levels by as much as 33%

Exactly,

very uncool!

which suprises me why people use it as it isnt that much cheaper then whey, if price is an issue pea protein is cheap and has a very valid amino profile.

The other thing is that Soy protein is the main protein in a lot of protein bars, BBs should always look at the type of protein in their bars, especially with this data!

you would never think to look at what protien is in a protien bar. now i shall look all the time -_-"

Jacob i'm not as clear on this issue as you are...so i'm basically asking what you think....i'm not a proponent of soy in the least bit, but isn't AMPK activated in response to resistance training in the healthy? I know they think chronic AMPK activation is one of the reasons why aged muscle doesn't hypertrophy...so i guess what i'm asking is, would the effects on mTOR from soy mostly depend upon how long AMPK is activated, acutely or chronically?

Good point, AMPK activation definately is strongly associated with decrements in hypertrophy in aged muscle.

AMPK is also activated with resistance training but this blunts the protein synthesis response to resistance training.

Nutritionally we can turn on AMPK a number of ways, but the main way appears to be by simply lowering the energetic state of the cell (glycogen depeltion) or in this case some component of the soy is actually able to activate AMPK, and thus it is hindering overall protein synthesis