matpal
03-19-2009, 08:11 PM
As featured in ULTIMA.
http://www.omegasportssupplements.com/web/index.php?option=com_content&view=article&id=70&Itemid=133
The Patented Creatine from Zone Halo Research and Medical Muscle.
Trinitine
Developed in conjunction with Dr. Dana Houser and Shawn Wells
Since its rapid rise in popularity in the 1990s, consumers and health enthusiasts alike have marveled at the wonders of creatine. Championed as the best-studied sports supplement ingredient, its reputation has vast amounts of support. However, this research continues to center on creatine monohydrate while neglecting various postulated creatine salts, which may hold additional ergogenic benefit.
One such salt, Magnesium Creatine Chelate (MCC), introduced to the industry by Albion Labs, has shown such promise while many of the alternative salts lack research support. Still, MCC alone is not without its own potential flaws that could render it less efficacious than it could be. As a result, the collective proposal of three creatine chelate salts holds potential to revolutionize a concept that will propel it to the forefront of the sports supplement industry.
Magnesium Creatine Chelate (MCC)
The first of three components to the Trinitine Complex, Magnesium Creatine Chelate (MCC) has been show in studies to improve exercise performance and allows athletes to reach exhaustion later in their exercise routine. This patented ingredient by Albion Labs is highly bioavailable and offers protection from the digestive tract. Protection from destruction in the digestive tract is crucial because it will make more creatine available for absorption in the body.
Eight percent of MCC is elemental magnesium. Magnesium is a macromineral that has many synergistic effects with creatine. In fact, ATP is actually found in the muscle cells bound to magnesium for stability. Taken on its own, magnesium has been shown to enhance strength and energy levels. It is intimately involved in the energy (Kreb's) cycle and has cardio-protective effects as well.
Creatine monohydrate has been shown to be very effective in hundreds of studies; however some users experience stomach discomfort due to lower absorption rate and breakdown into its by-product creatinine in the stomach. By creating a creatine-magnesium chelate, creatine can be protected from the harsh environment of the stomach acid and this chelate can help prevent breakdown. It can also help enhance absorption of creatine and decrease stomach discomfort that many creatine users (and their friends) can appreciate. This chelation provides a highly bioavailable form of creatine and magnesium.
Initial research shows MCC is better absorbed and tolerated than traditional creatine monohydrate supporting more explosive gains in muscle size, strength, and endurance. Further still, when compared with creatine monohydrate groups and various magnesium salts, you also get significant increased levels of absorption with the MCC than either component alone. As a result, you harness the ergogenic power of both creatine and magnesium:
Supercharging strength and power output
Prolonging endurance activity
Speeding muscle recovery
Reducing fatigue
Increasing muscle size and volumization
Enhancing ATP preservation and recovery
Maximizing creatine storage and uptake into muscle
It also mixes well in water. There have been no side effects shown with this compound at the recommended doses and it shows excellent promise for the future of creatine.
Still, there is one potential consideration that must be considered with various ions added into the equation. A potential offset of the homeostatic mechanisms will render the entire process useless if taken out of significant proportion. If magnesium concentration is higher than that of ATP, magnesium inhibited the ATPase and simultaneously stimulated the phosphatase. Increasing the concentration of magnesium directly causes a change in the conformation of the enzyme which favors ATPase activity to one which favors phosphatase activity.
http://img34.picoodle.com/img/img34/3/2/18/f_graphm_3206474.jpg
The potential remedy to this potential downfall lies in a sodium and potassium ratio that would offset potential inactivation of the ATPase. Enter KCC and NaCC.
Potassium Creatine Chelate (KCC) and Sodium Creatine Chelate (NaCC)
Primary active transport carriers are often referred to as pumps. Although some of these carriers transport only one molecule or ion at a time, others exchange one molecule or ion for another. The most important of this latter type of carrier is the Na+/K+-ATPase or pump. This carrier protein, which is also an ATPase enzyme that converts ATP to ADP + Pi, actively extrudes three sodium ions (Na+) from the cell as it transports two potassium ions (K+) into the cell. The transport is energy dependent because Na+ is more highly concentrated outside the cell and K+ is more concentrated within the cell. Both ions, in other words, are moved against their concentration gradients.
http://www.omegasportssupplements.com/web/index.php?option=com_content&view=article&id=70&Itemid=133
The Patented Creatine from Zone Halo Research and Medical Muscle.
Trinitine
Developed in conjunction with Dr. Dana Houser and Shawn Wells
Since its rapid rise in popularity in the 1990s, consumers and health enthusiasts alike have marveled at the wonders of creatine. Championed as the best-studied sports supplement ingredient, its reputation has vast amounts of support. However, this research continues to center on creatine monohydrate while neglecting various postulated creatine salts, which may hold additional ergogenic benefit.
One such salt, Magnesium Creatine Chelate (MCC), introduced to the industry by Albion Labs, has shown such promise while many of the alternative salts lack research support. Still, MCC alone is not without its own potential flaws that could render it less efficacious than it could be. As a result, the collective proposal of three creatine chelate salts holds potential to revolutionize a concept that will propel it to the forefront of the sports supplement industry.
Magnesium Creatine Chelate (MCC)
The first of three components to the Trinitine Complex, Magnesium Creatine Chelate (MCC) has been show in studies to improve exercise performance and allows athletes to reach exhaustion later in their exercise routine. This patented ingredient by Albion Labs is highly bioavailable and offers protection from the digestive tract. Protection from destruction in the digestive tract is crucial because it will make more creatine available for absorption in the body.
Eight percent of MCC is elemental magnesium. Magnesium is a macromineral that has many synergistic effects with creatine. In fact, ATP is actually found in the muscle cells bound to magnesium for stability. Taken on its own, magnesium has been shown to enhance strength and energy levels. It is intimately involved in the energy (Kreb's) cycle and has cardio-protective effects as well.
Creatine monohydrate has been shown to be very effective in hundreds of studies; however some users experience stomach discomfort due to lower absorption rate and breakdown into its by-product creatinine in the stomach. By creating a creatine-magnesium chelate, creatine can be protected from the harsh environment of the stomach acid and this chelate can help prevent breakdown. It can also help enhance absorption of creatine and decrease stomach discomfort that many creatine users (and their friends) can appreciate. This chelation provides a highly bioavailable form of creatine and magnesium.
Initial research shows MCC is better absorbed and tolerated than traditional creatine monohydrate supporting more explosive gains in muscle size, strength, and endurance. Further still, when compared with creatine monohydrate groups and various magnesium salts, you also get significant increased levels of absorption with the MCC than either component alone. As a result, you harness the ergogenic power of both creatine and magnesium:
Supercharging strength and power output
Prolonging endurance activity
Speeding muscle recovery
Reducing fatigue
Increasing muscle size and volumization
Enhancing ATP preservation and recovery
Maximizing creatine storage and uptake into muscle
It also mixes well in water. There have been no side effects shown with this compound at the recommended doses and it shows excellent promise for the future of creatine.
Still, there is one potential consideration that must be considered with various ions added into the equation. A potential offset of the homeostatic mechanisms will render the entire process useless if taken out of significant proportion. If magnesium concentration is higher than that of ATP, magnesium inhibited the ATPase and simultaneously stimulated the phosphatase. Increasing the concentration of magnesium directly causes a change in the conformation of the enzyme which favors ATPase activity to one which favors phosphatase activity.
http://img34.picoodle.com/img/img34/3/2/18/f_graphm_3206474.jpg
The potential remedy to this potential downfall lies in a sodium and potassium ratio that would offset potential inactivation of the ATPase. Enter KCC and NaCC.
Potassium Creatine Chelate (KCC) and Sodium Creatine Chelate (NaCC)
Primary active transport carriers are often referred to as pumps. Although some of these carriers transport only one molecule or ion at a time, others exchange one molecule or ion for another. The most important of this latter type of carrier is the Na+/K+-ATPase or pump. This carrier protein, which is also an ATPase enzyme that converts ATP to ADP + Pi, actively extrudes three sodium ions (Na+) from the cell as it transports two potassium ions (K+) into the cell. The transport is energy dependent because Na+ is more highly concentrated outside the cell and K+ is more concentrated within the cell. Both ions, in other words, are moved against their concentration gradients.