View Full Version : BCAAs and sleep
02-05-2007, 04:05 AM
Recently I've experimenting with 7-10 grams of BCAAs in the middle of the night, and find that it's been upsetting my sleep (can't get back to sleep). I only take them if I wake up naturally (to go to the bathroom).
I have often done middle-of-the-night WP shakes without noticing these problems.
I have a theory, though -- and I'm seeing some anecdotal support on other forums about parts of it.
Here's the thing. We all know that BCAAs = rise in insulin. So when in a fasted state (like middle of the night)...
BCAAs = insulin spike (w/o much glucose) = hypoglycemia = catecholamine release to compensate for hypoglycemia = simultaneous lipolysis and proteogenesis (if the plasma aminos are enough to drown out the catecholamine proteolysis problem), but no ZZZZZs.
What do you guys think? Anyone have any related issues?
02-05-2007, 05:41 AM
It is a possibility, and I like your thinking. What you might do is combine it with fish oil pills to slow down its digestion. that should solve the problem
02-05-2007, 01:16 PM
Thanks for the response, Pres! Do you think that the anabolic benefit would be decreased at all by slowing the absorption time?
02-05-2007, 03:09 PM
Gosh, you guys are geniuses! /forum/images/graemlins/cool.gif
02-07-2007, 02:14 AM
the rate of protein synthesis may be somewhat slowed, but because the aminos are so rapidly digested anyway, you should get a similar anabolic response.
In fact, one of the issues with the high rate of absorbtion is that a proportion of those amino acids will be used as fuel. When fats are added this has a sparing effect, so in reality, it could be more anabolic
02-07-2007, 03:46 AM
Speaking of digestion/absorption rates, what do you think of these ideas that I've come across recently:
Whey hydrosylate (spl) is "faster" than BCAAs because a protein transport mechanism is better adapted to peptides than individual ("pre-digested") aminos...
Legumes should be avoided because of their protease inhibitors leading to poor digestion/absorption of PRO...
and (non-protein containing) liquid volume should be kept to a minimum during meal time (outside of meal time, HYDRATE!) to maximize the substrate (PRO) concentration. This month in Biochem we were introduced to Michaelis-Menton kinetics, and if this situation applies, catalysis rate would definitely be optimized by maxing out [S] (by keeping non-S volume to a minimum).
Sorry 'bout all these Qs... I just see these things that make sense, but doing a little of my own investigating hasn't yielded anything in reference to the first two at all. Nothing "scientific," at least.
Edit: upon rereading that last Q, let me rephrase for clarity:
Don't drink much water with your PRO meals because dilution issues can make protease-mediated catalysis slower.
vBulletin® v3.7.2, Copyright ©2000-2013, Jelsoft Enterprises Ltd.